In the 1990s, the Dean of the then Faculty of Agriculture of the University of Ghana, Emeritus Professor E. V. Doku, initiated discussion on the possibility of training veterinary surgeons in Ghana. For many years, various stakeholder groups including the Ghana Veterinary Medical Association (GVMA), the Veterinary Council of Ghana and some Senior Members belonging to the veterinary profession, including the late Professors E N W Oppong and R Assoku, suggested the establishment of a School of Veterinary Medicine within the University of Ghana. For a variety of reasons, this did not materialize.

In January 2006, the Veterinary Council of Ghana requested the University of Ghana to consider establishing a School of Veterinary Medicine for the training of veterinarians in Ghana. The National Council for Tertiary Education gave approval in principle for the establishment of the School in the 2008/2009 Academic Year, subject to the details being approved by the Academic Board. The process could not be completed early enough for the programme to start in the 2008/2009 Academic Year as planned. However, the first batch of 10 students enrolled in the 2009/10 Academic Year for the 6-year DVM programme and graduated in June 2015. Over the years we have graduated on average 12 students per year.